Lichen planus and nanocurcumin

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A randomized, placebo-controlled, double-blind clinical trial of curcuminoids in oral lichen planus.

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Possible action mechanism for curcumin in pre-cancerous lesions based on serum and salivary markers of oxidative stress.

Rai B, Kaur J, Jacobs R, Singh J.J Oral Sci. 2010 Jun;52(2):251-6. doi: 10.2334/josnusd.52.251.

High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus.

Chainani-Wu N, Madden E, Lozada-Nur F, Silverman S Jr.J Am Acad Dermatol. 2012 May;66(5):752-60. doi: 10.1016/j.jaad.2011.04.022. Epub 2011 Sep 9.PMID: 21907450 Clinical Trial.

Use of curcuminoids in a cohort of patients with oral lichen planus, an autoimmune disease.

Chainani-Wu N, Collins K, Silverman S Jr.Phytomedicine. 2012 Mar 15;19(5):418-23. doi: 10.1016/j.phymed.2011.11.005. Epub 2012 Feb 2.PMID: 22305276 Clinical Trial.

Turmeric - A new treatment option for lichen planus: A pilot study.

Singh V, Pal M, Gupta S, Tiwari SK, Malkunje L, Das S.Natl J Maxillofac Surg. 2013 Jul;4(2):198-201. doi: 10.4103/0975-5950.127651.

Comparative Efficacy of Topical Curcumin and Triamcinolone for Oral Lichen Planus: A Randomized, Controlled Clinical Trial.

Evaluation of the Efficacy of Curcumin in the Treatment of Oral Lichen Planus: A Randomized Controlled Trial.

Amirchaghmaghi M, Pakfetrat A, Delavarian Z, Ghalavani H, Ghazi A.J Clin Diagn Res. 2016 May;10(5):ZC134-7. doi: 10.7860/JCDR/2016/16338.7870. Epub 2016 May 1.

Comparison of the Effects of Curcumin Mucoadhesive Paste and Local Corticosteroid on the Treatment of Erosive Oral Lichen Planus Lesions.

Evaluation of Efficacy of 1% Curcuminoids as Local Application in Management of Oral Lichen Planus - Interventional Study.

Thomas AE, Varma B, Kurup S, Jose R, Chandy ML, Kumar SP, Aravind MS, Ramadas AA.J Clin Diagn Res. 2017 Apr;11(4):ZC89-ZC93. doi: 10.7860/JCDR/2017/20898.9715. Epub 2017 Apr 1.PMID: 28571271 Free PMC article.

INTRODUCTION: Oral Lichen Planus (OLP) is a chronic inflammatory mucocutaneous disease affecting the oral cavity which has been associated with severe burning sensation which in turn affects the quality of life of the patients. ...Hence, this intervention study was …

Curcumin, a turmeric extract, for oral lichen planus: A systematic review.

White CM, Chamberlin K, Eisenberg E.Oral Dis. 2019 Apr;25(3):720-725. doi: 10.1111/odi.13034. Epub 2019 Jan 25.PMID: 30614166

Clinical safety and efficacy of curcumin use for oral lichen planus: a systematic review.

Lv KJ, Chen TC, Wang GH, Yao YN, Yao H.J Dermatolog Treat. 2019 Sep;30(6):605-611. doi: 10.1080/09546634.2018.1543849. Epub 2018 Nov 28.

Comparison of oral Nano-Curcumin with oral prednisolone on oral lichen planus: a randomized double-blinded clinical trial.

Kia SJ, Basirat M, Mortezaie T, Moosavi MS.BMC Complement Med Ther. 2020 Oct 31;20(1):328. doi: 10.1186/s12906-020-03128-7.

Curcuma Longa in the Treatment of Symptomatic oral lichen planus: A non-randomized controlled trial.

Is Curcumin a Safe and Effective Therapeutic in the Treatment against Oral Lichen Planus?

Khosrojerdi M, Gumpricht E, Jamialahmadi T, Kesharwani P, Sahebkar A.Curr Med Chem. 2023;30(15):1684-1688. doi: 10.2174/0929867330666221202150727.

Effects of Curcumin on the treatment of oral lichen planus symptoms: a systematic review and meta-analysis study.

Moayeri H, Rajabi A, Mohammadi M, Moghaddam SB.BMC Oral Health. 2024 Jan 17;24(1):104. doi: 10.1186/s12903-024-03873-y.

Curcumin Versus Corticosteroids for Symptomatic Oral Lichen Planus: A Systematic Review and Meta-Analysis.

Al-Maweri SA, Al-Qadhi G, Alqutaibi AY, Sallam NM, Assad M, Abdulghani MA, Mohammed MMA.Clin Exp Dent Res. 2025 Oct;11(5):e70227. doi: 10.1002/cre2.70227.

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