Psoriasis and nanocurcumin

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Curcumin: a novel treatment for skin-related disorders.

Nguyen TA, Friedman AJ.J Drugs Dermatol. 2013 Oct;12(10):1131-7.

Beneficial role of curcumin in skin diseases.

Thangapazham RL, Sharma A, Maheshwari RK.Adv Exp Med Biol. 2007;595:343-57. doi: 10.1007/978-0-387-46401-5_15.

Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.

Efficacy and safety of curcumin in psoriasis: preclinical and clinical evidence and possible mechanisms.

Zhang S, Wang J, Liu L, Sun X, Zhou Y, Chen S, Lu Y, Cai X, Hu M, Yan G, Miao X, Li X.Front Pharmacol. 2022 Aug 29;13:903160. doi: 10.3389/fphar.2022.903160. eCollection 2022.

Curcumin shows excellent therapeutic effect on psoriasis in mouse model.

Kang D, Li B, Luo L, Jiang W, Lu Q, Rong M, Lai R.Biochimie. 2016 Apr;123:73-80. doi: 10.1016/j.biochi.2016.01.013. Epub 2016 Jan 27.

but of course, humans are not mice!

So what do human trials of curcumin in psoriasis show?

Oral curcumin in the treatment of moderate to severe psoriasis vulgaris: A prospective clinical trial.

Effects of Curcuma extract and visible light on adults with plaque psoriasis.

Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris.

Curcumin nanoparticles potentiate therapeutic effectiveness of acitrein in moderate-to-severe psoriasis patients and control serum cholesterol levels.

Niosomal Curcumin Suppresses IL17/IL23 Immunopathogenic Axis in Skin Lesions of Psoriatic Patients: A Pilot Randomized Controlled Trial.

Review

Use of Curcumin in Psoriasis.

Nardo VD, Gianfaldoni S, Tchernev G, Wollina U, Barygina V, Lotti J, Daaboul F, Lotti T.Open Access Maced J Med Sci. 2018 Jan 21;6(1):218-220. doi: 10.3889/oamjms.2018.055. eCollection 2018 Jan 25.

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