Evidence-Based Fertility Supplements: Nutrients for Egg Quality to support natural fertility in women with low AMH
Written by fertility nutrition expert, Dr. Conor Kerley
Dr. Conor Kerley is a multi-award winning nutrition researcher, leading clinician as well as a member of the European Fertility Society and European Society of Human Reproduction and Embryology (ESHRE).
What is AMH
Anti‑Müllerian hormone (AMH) is a hormone related to reproductive function, mainly used to evaluate ovarian reserve (how many eggs remain in the ovaries).
What AMH does
- AMH is produced by small follicles in the ovaries (the sacs that contain immature eggs).
- The level of AMH in blood roughly reflects the number of remaining eggs.
- Doctors often measure AMH with a blood test.
Why do doctors check AMH?
AMH testing is commonly used for:
- Fertility evaluation – estimating ovarian reserve.
- IVF planning – predicting how the ovaries may respond to fertility medications.
- Diagnosing conditions like Polycystic Ovary Syndrome (often higher AMH).
- Assessing menopause timing – AMH typically declines as menopause approaches.
What do AMH results mean?
AMH values vary by lab, but roughly:
- High AMH: large ovarian reserve (sometimes seen in PCOS)
- Normal AMH: average egg reserve
- Low AMH: reduced ovarian reserve
AMH results depend on the woman’s age:
|
Age |
Typical AMH range |
|
20-24 |
3 to 6 |
|
25-29 |
2.5 to 5 |
|
30-34 |
1.5 to 4 |
|
35-39 |
1 to 3 |
|
40-44 |
0.5 to 2 |
|
45+ |
0.1 to 0.5 |
General interpretation
-
High AMH (>4 ng/mL)
May indicate high ovarian reserve; sometimes associated with Polycystic Ovary Syndrome (PCOS) -
Normal AMH (1–4 ng/mL)
Typical ovarian reserve for many reproductive-age women. -
Low AMH (<1 ng/mL)
Suggests reduced ovarian reserve. -
Very low AMH (<0.5 ng/mL)
Often seen closer to menopause or in significantly diminished ovarian reserve.
Important: AMH does NOT measure egg quality, only the approximate quantity.
Key facts
- AMH can be tested any day of the menstrual cycle.
- Levels naturally decline with age.
- A low AMH does not necessarily mean you cannot get pregnant.
- Some women with low AMH still conceive naturally.
What If Your AMH Is Low?
Receiving a low AMH result can be worrying.
However, AMH is only one piece of the fertility puzzle.
Factors that also influence fertility include:
- egg quality
- ovulation
- sperm health
- uterine health
- hormone balance
Many women with low AMH still achieve pregnancy with the right lifestyle, nutritional support and medical care.
Lifestyle Factors That Affect AMH and Fertility
Include:
- smoking
- BMI
- sleep
- stress
- environmental toxins
Emerging human research suggests that certain nutrients may influence ovarian function and AMH levels.
Therefore specific nutrients in specific doses offer support for women with low AMH.
Fertility supplements for conception in women with low AMH levels
The nutrients which have been shown in human research studies in women with low AMH to increase AMH levels include:
Selenium and vitamin E
in a 2021 study women who took 200mcg selenium + vitamin E for 3 months had significant increases in AMH
Vitamin d
a 2017 study and a separate 2018 study reported that vitamin D supplementation could increase AMH levels. ‘The research wrote: Vitamin Ds positive effects on the fertility of woman may involve the regulation of ovarian AMH levels’
A 2017 study examined the effect of combined supplementation for 4 months with N Acetyl cystine (NAC), zinc and vitamins B2, B6, B9 and B12 and reported a 40% increase in AMH levels
A 2022 study examined the effect of combined supplementation with:
coenzyme Q10,
vitamin E,
vitamin b9 (folic acid),
selenium,
green tea extract,
on AMH levels and endometrial thickness values. The combined supplement led to an increase in AMH of 31%
Coenzyme Q10
We know coenzyme Q10 is very important for overall fertility but a 2018 study suggests that coenzyme Q10 may not be beneficial for increasing AMH level.
Collectively, these 12 nutrients may help increase AMH levels
Because these 12 nutrients are backed by specific research in women with low AMH levels, they represent the best supplements for women with low AMH,
Women with low AMH who are trying to conceive should consider targeted metabolic and mitochondrial support including supplementing these 12 nutrients alongside key preconception nutrients such as alpha lipoic acid, carnitine and iodine.
Why Egg Quality Matters More Than AMH
research-backed doses matter. But combining these individual nutrients correctly can be complex, requiring multiple supplements and careful dosing.
Why Fertility Phix Combines These Nutrients
Many of the nutrients shown to support AMH levels are found in separate supplements.
This can make it difficult to achieve the research-backed doses used in clinical studies.
Women often end up taking 5–8 different supplements to replicate these protocols. In fact, I remember seeing a lady at my clinic in Dublin taking 35 fertility supplements every single day! Other people have called themselves walking pharmacies due to the amount of fertility supplements being taken daily.
It combines evidence-informed doses of these key nutrients into a single daily fertility formula, alongside additional compounds that support:
· egg quality
· mitochondrial function
· hormone balance
Fertility Phix is an all in one fertility supplement and was formulated to provide these research-backed nutrients in evidence-informed doses, alongside additional compounds that support egg quality and mitochondrial function and hormone balance. Fertility Phix has already helped several women with low AMH levels to increase their AMH – check out these reviews:
If you have low AMH and are trying to conceive, targeted nutritional support may be a valuable part of your strategy. Explore Fertility Phix here or contact us to discuss whether it is right for you.
Who is Fertility Phix suitable for?
Anybody on a fertility journey who wants to provide themselves with a comprehensive mix of research backed nutrients
When to start Fertility Phix?
Lifestyle changes, including supplements are recommended for at least 3 months before conception. This is because a woman’s eggs take approximately 3 to 4 months (roughly 90-120 days) to mature -this is why we offer a 3 month bundle where if you add 3 boxes Fertility Phix sachets to your cart, you save a massive 60 euro and get free shipping anywhere in the world!
Key Takeaways
AMH is a hormone used to estimate ovarian reserve.
• AMH declines naturally with age but does not measure egg quality.
• Many women with low AMH still conceive naturally.
• Emerging research suggests certain nutrients (NAC, green tea extract, selenium, B vitamins, vitamin D vitamin E ) may support ovarian health and AMH levels.
• Nutritional strategies should begin at least 3 months before trying to conceive.
Frequently asked questions
Can You Get Pregnant with Low AMH?
Yes! Many women with low AMH conceive naturally. Remember, AMH is just one key fertility hormone which can help doctors estimate how many eggs you have. But AMH levels to not tell us anything about egg quality. And only one egg is needed for successful. However, low AMH can indicate a shorter reproductive window, which is why many clinicians recommend optimising fertility sooner rather than later.fertilization and pregnancy
Note, regardless of PCOS, fertility issues are NOT female only. Approximately 40–50% of infertility cases involve male factors. These figures highlight the importance of assessing both partners and the importance of a healthy fertility supportive lifestyle for both partners.
If you are a woman trying to conceive, make sure your male partner has been tested, is following a fertility friendly lifestyle and check our these blogs:
Nutrients for Male Fertility, Sperm Quality and sperm count - The Science
Nutrients for Male Fertility, Sperm Quality and sperm motility - The Science
Nutrients for Male Fertility, Sperm Quality and sperm morphology - The Science
Nutrients for Male Fertility, Sperm Quality and sperm DNA fragmentation - The Science
Nutrients for Male Fertility, Sperm Quality and varicocele - The Science
In addition to low AMH, other common conditions contributing to fertility issues in women, include:
Advanced age
Antiphospholipid syndrome
Endometriosis
Fibroids
Hypothalamic amenorrhea
Lupus
Premature ovarian insufficiency (POI)
Thyroid issues, especially Hashimoto's or autoimmune thyroiditis
Please note: This article is for educational purposes only and does not replace personalised medical advice. Nutritional strategies support ovulatory function but do not replace ovulation induction medications (e.g., letrozole) when clinically indicated.
· Not all supplements are appropriate for everyone. Always consult your GP or fertility specialist before starting supplements, particularly if undergoing assisted reproductive treatment.
· Timing matters – lifestyle changes, including supplements are recommended for at least 3 months before conception. This is because a woman’s eggs take approximately 3 to 4 months (roughly 90-120 days) to mature before ovulation, in a process known as folliculogenesis.
· Dosing matters – scientific research has reported benefits of certain doses. It is important to seek out and consume these doses to get the same benefits.
